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Potential of Soursop Leaf Extract Scrub as Antimicrobial
Treatment of infectious diseases caused by bacteria has been carried out using
antibiotics. However, the problem is resistance and even multi-resistance in bacteria.
Preventive efforts are needed to anticipate, one of which is using soursop leaf extract
scrub herbal products which contain gamma oryzanol compounds, flavonoids, phenols,
and tannins as antimicrobials. This research is a pure experiment with one group pretest-
posttest control design and positive and negative controls. The study aims to analyse the
effectiveness of soursop leaf extract scrub products as antimicrobials on the skin of the
respondents' arms before and after treatment. Antimicrobial counting uses the total plate
count (TPC) method, with 118 respondents in-vivo, where the scrub is applied to the
respondent's arm, measuring 10cm x 10cm for 10 minutes. The results of the data
normality test with the Kolmogorov-Smirnov test obtained non-normally distributed data.
The trial continued with a non-parametric test in the Wilcoxon test to get a significance
value of 0.000
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