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Chemotherapy-Induced Nausea and Vomiting (CINV) Based on Blood Types among Cancer Patients in Yogyakarta, Indonesia

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Background: Studies related to blood type in cancer patients have been conducted
extensively, but they are inclined to cancer incidence or survival rate. Meanwhile,
there is limited research on Chemotherapy-Induced Nausea and Vomiting (CINV),
the most disturbing side effect of chemotherapy, in relation to blood type.
Purpose: This study aimed to compare CINV frequency in cancer patients by blood
groups in Yogyakarta, Indonesia.
Methods: A descriptive comparative study with a cross-sectional approach was
conducted purposively on 70 chemotherapy patients in two hospitals in Yogyakarta.
Patients with anticipatory CINV and brain cancer (primary or metastases) were
excluded. The data were collected between July and November 2020 using a sheet

for patient characteristics and a filled-in diary from the first to the seventh day post-
chemotherapy to collect CINV data. The descriptive statistics and Kruskal Wallis test

were used to analyze the data.
Results: Of 70 total samples, most of them were breast cancer (71.4%) and were in
stage IV (50%). They received chemotherapy alone as their primary therapy (94.3%)
and received moderate to high emetogenic agents (31.4% and 35.7%). Samples
mostly had A blood type (34.3%) and had undergone chemotherapy for 3-18 months
(min-max). As many as 64.6% of patients experienced CINV with a delayed type and
experienced moderate severity (52.9%). The bivariate test showed no difference in
CINV frequencies based on blood groups in general (p=0.068). However, based on
the CINV onset, there was a significant difference in CINV frequencies in the A blood
group against other blood groups (p=0.020) on the fourth post-chemotherapy day.
Conclusions: Unless the fourth-day post-chemotherapy, the frequency of CINV

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Informasi Detail

Judul Seri

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No. Panggil

10

Penerbit

: .,

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

2406-8799,

Klasifikasi

NONE

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

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Info Detail Spesifik

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Pernyataan Tanggungjawab

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